PiDiOne^TM is a high precision, non-contact piezo micro-dispensing system, designed with flexibility in mind. The system quantitatively dispenses very low (sub-nanolitre) volumes of biological samples in user-designed experiments, utilising simple, easy-to-use software. PiDiOne^TM is extremely accurate, with precision controlled sample deposition resulting in accurate and reproducible sample volume and position, every time. Besides significantly reducing contamination possibilities, another advantage of using PiDiOne^TM's non-contact piezo technology is that only minimal sample volume is required for operation, conserving your rare or precious samples. PiDiOne^TM is flexible in its function; being a cost effective option for personal research yet also capable of handling large numbers of samples quickly and efficiently in a high throughput operation. The system is highly automated in every aspect, from substrate recognition to 3-dimensional droplet analysis and control; making PiDiOne the choice for all your micro-dispensing needs.